| |
Treatment
|
Treatment difference
|
|---|
| |
LSM ± SEM
|
LSM ± SEM
|
|---|
|
Change from baseline in the mean daily number of puffs of rescue medication
|
|
Indacaterol 150 μg o.d.
|
-1.38 ± 0.118
| |
| | |
-0.97 ± 0.168*
|
|
Placebo
|
-0.41 ± 0.122
| |
|
Change from baseline in the mean day time number of puffs of rescue medication
|
|
Indacaterol 150 μg o.d.
|
-0.92 ± 0.076
| |
| | |
-0.65 ± 0.109*
|
|
Placebo
|
-0.27 ± 0.079
| |
|
Change from baseline in the mean night time number of puffs of rescue medication
|
|
Indacaterol 150 μg o.d.
|
-0.47 ± 0.052
| |
| | |
-0.34 ± 0.075*
|
|
Placebo
|
-0.13 ± 0.054
| |
|
Percentage of days with no rescue use
|
|
Indacaterol 150 μg o.d.
|
54.63 ± 1.942
| |
| | |
13.35 ± 2.791*
|
|
Placebo
|
41.28 ± 2.004
| |
|
Percentage of COPD 'days of poor control'
|
|
Indacaterol 150 μg o.d.
|
31.19 ± 1.500
| |
| | |
-9.05 ± 2.175*
|
|
Placebo
|
40.24 ± 1.554
| |
- COPD = chronic obstructive pulmonary disease; ITT = intent-to-treat;
- LSM = least squares mean; SEM = standard error of the mean
- * p < 0.001
