Table 3 Rescue medication use and percentage of COPD 'days of poor control' over 12 weeks of treatment (ITT population)
Treatment | Treatment difference | |
|---|---|---|
LSM ± SEM | LSM ± SEM | |
Change from baseline in the mean daily number of puffs of rescue medication | ||
Indacaterol 150 μg o.d. | -1.38 ± 0.118 | |
-0.97 ± 0.168* | ||
Placebo | -0.41 ± 0.122 | |
Change from baseline in the mean day time number of puffs of rescue medication | ||
Indacaterol 150 μg o.d. | -0.92 ± 0.076 | |
-0.65 ± 0.109* | ||
Placebo | -0.27 ± 0.079 | |
Change from baseline in the mean night time number of puffs of rescue medication | ||
Indacaterol 150 μg o.d. | -0.47 ± 0.052 | |
-0.34 ± 0.075* | ||
Placebo | -0.13 ± 0.054 | |
Percentage of days with no rescue use | ||
Indacaterol 150 μg o.d. | 54.63 ± 1.942 | |
13.35 ± 2.791* | ||
Placebo | 41.28 ± 2.004 | |
Percentage of COPD 'days of poor control' | ||
Indacaterol 150 μg o.d. | 31.19 ± 1.500 | |
-9.05 ± 2.175* | ||
Placebo | 40.24 ± 1.554 | |