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Table 1 Clinical characteristics at baseline and during the study

From: The prevalence of anemia and its association with 90-day mortality in hospitalized community-acquired pneumonia

  

ICU Admission

Severe Sepsis

Comorbidity

 

All

Yes

No

Yes

No

Yes

No

N

1893

303

(16.0)

1590

(84.0)

582

(30.7)

1311

(69.3)

1373

(72.5)

520

(27.5)

Age, years, mean (SD)

67.8

(16.8)

68.1

(15.7)

67.7

(17.0)

71.5

(15.7)

66.1

(17.0)

69.9

(15.3)

62.2

(19.1)

Male gender, n (%)

983

(51.9)

168

(55.4)

815

(51.3)

329

(56.5)

654

(49.9)

738

(53.8)

245

(47.1)

Race, n (%)

       

   White

1527

(80.7)

245

(80.9)

1282

(80.6)

494

(84.9)

1033

(78.8)

1121

(81.6)

406

(78.1)

   Black

299

(15.8)

51

(16.8)

248

(15.6)

73

(12.5)

226

(17.2)

206

(15.0)

93

(17.9)

   Other

67

(3.5)

7

(2.3)

60

(3.8)

15

(2.6)

52

(4.0)

46

(3.4)

21

(4.0)

Underlying diseasea

       

   Charlson comorbidity >0, n (%)

1373

(72.5)

225

(74.3)

1148

(72.2)

446

(76.6)

927

(70.7)

1373

(100.0)

n/a

   Charlson comorbidity, mean (SD)

1.9

(2.2)

1.9

(2.2)

1.9

(2.2)

2.2

(2.3)

1.8

(2.2)

2.7

(2.2)

n/a

   Cardiovascular disease, n (%)

487

(25.7)

79

(26.1)

408

(25.7)

163

(28.0)

324

(24.7)

487

(35.5)

n/a

   Respiratory disease, n (%)

717

(37.9)

118

(38.9)

599

(37.7)

207

(35.6)

510

(38.9)

717

(52.2)

n/a

   Chronic hemodialysis, n (%)

48

(2.5)

11

(3.6)

37

(2.3)

9

(1.5)

39

(3.0)

48

(3.5)

n/a

   Cirrhosis, n (%)

5

(0.3)

1

(0.3)

4

(0.3)

1

(0.2)

4

(0.3)

5

(0.4)

n/a

PSI, mean (SD)

99.8

(38.1)

124.2

(40.7)

95.1

(35.8)

121.2

(40.4)

90.3

(32.9)

106.8

(37.8)

81.4

(32.3)

PSI class, n (%)

       

   I and II

428

(22.6)

26

(8.6)

402

(25.3)

55

(9.5)

373

(28.5)

216

(15.7)

212

(40.8)

   III

392

(20.7)

35

(11.6)

357

(22.5)

76

(13.1)

316

(24.1)

265

(19.3)

127

(24.4)

   IV

708

(37.4)

116

(38.3)

592

(37.2)

230

(39.5)

478

(36.5)

571

(41.6)

137

(26.3)

   V

365

(19.3)

126

(41.6)

239

(15.0)

221

(38.0)

144

(11.0)

321

(23.4)

44

(8.5)

APACHE III, mean (SD)

56.1

(17.9)

67.7

(20.5)

53.9

(16.4)

65.8

(19.8)

51.8

(15.1)

58.6

(17.6)

49.4

(16.8)

SOFA, mean (SD)

2.4

(1.9)

3.7

(2.7)

2.2

(1.7)

3.7

(2.4)

1.8

(1.3)

2.5

(2.1)

2.1

(1.6)

Duration of symptoms prior to ED presentation, daysb, mean (SD)

4.9

(7.1)

4.7

(6.8)

5.0

(7.2)

4.9

(7.6)

5.0

(6.9)

4.8

(7.2)

5.3

(7.0)

Antibiotics before presentation, n (%)

333

(17.6)

57

(18.8)

276

(17.4)

93

(16.0)

240

(18.3)

233

(17.0)

100

(19.2)

Transfusion in hospital, n (%)

176

(9.3)

97

(32.0)

79

(5.0)

125

(21.5)

51

(3.9)

138

(10.1)

38

(7.3)

ICU admission, n (%)

303

(16.0)

303

(100.0)

n/a

225

(38.7)

78

(5.9)

225

(16.4)

78

(15.0)

Mechanical ventilation, n (%)

132

(7.0)

123

(40.6)

9

(0.6)

132

(22.7)

0

(0.0)

89

(6.5)

43

(8.3)

Hospital length of stay, days, mean (SD)

7.3

(5.0)

12.7

(7.2)

6.3

(3.6)

10.3

(6.7)

6.0

(3.3)

7.5

(4.9)

7.0

(5.3)

Hospital mortality, n (%)

87

(4.6)

53

(17.5)

34

(2.1)

83

(14.3)

4

(0.3)

71

(5.2)

16

(3.1)

90-day mortality, n (%)

215

(11.4)

80

(26.4)

135

(8.5)

150

(25.8)

65

(5.0)

184

(13.4)

31

(6.0)

  1. PSI, Pneumonia Severity Index; SOFA, Sequential Organ Failure Assessment; APACHE III, Acute Physiology and Chronic Health Evaluation III score; ED, Emergency Department; ICU, intensive care unit.
  2. aAccording to the method of Charlson et al [22]
  3. b Missing for 19 subjects