Positive Association between Aspirin-Intolerant Asthma and Genetic Polymorphisms of FSIP1: a Case-Case Study

BMC Pulmonary Medicine

Table 2 Logistic and statistical analyses of FSIP1 SNPs in haplotype block 1.

rs#	Position	MAF			Heterozygosity	HWE	OR(95%CI)	P	P ^cor.
		AIA	ATA	Total
rs1602543	Intron2	0.199	0.235	0.226	0.350	0.997	0.81 (0.59-1.11)	0.19	1.00
rs7179742	Intron2	0.358	0.262	0.287	0.409	0.765	1.63 (1.23-2.16)	0.0007	0.03
rs1021411	Intron3	0.292	0.227	0.242	0.367	0.885	1.47 (1.09-1.98)	0.01	0.55
rs1021410	Intron3	0.352	0.262	0.284	0.407	0.751	1.60 (1.20-2.13)	0.001	0.06
rs12440567	Intron3	0.325	0.240	0.261	0.386	0.788	1.58 (1.18-2.10)	0.002	0.09
rs2576932	Intron3	0.443	0.508	0.490	0.500	0.786	0.75 (0.58-0.98)	0.03	1.00
rs10520151	Intron5	0.027	0.023	0.024	0.047	0.274	1.17 (0.53-2.59)	0.70	1.00
rs16969802	Intron5	0.322	0.239	0.260	0.384	0.705	1.56 (1.17-2.08)	0.002	0.11
rs12911842	Intron5	0.211	0.260	0.242	0.367	0.467	0.73 (0.54-0.99)	0.04	1.00
rs7179417	Intron5	0.446	0.509	0.492	0.500	0.815	0.76 (0.59-0.98)	0.04	1.00
rs4115216	Intron5	0.446	0.510	0.493	0.500	0.877	0.76 (0.58-0.98)	0.03	1.00
rs8033957	Intron5	0.527	0.468	0.485	0.500	0.511	1.28 (1.00-1.66)	0.05	1.00
rs6492915	Intron5	0.527	0.468	0.485	0.500	0.511	1.28 (1.00-1.66)	0.05	1.00
rs8031241	Intron5	0.452	0.513	0.497	0.500	0.905	0.76 (0.59-0.99)	0.04	1.00
rs1906164	Intron6	0.232	0.249	0.247	0.372	0.852	0.91 (0.67-1.23)	0.53	1.00

MAF, minor allele frequency; AIA, aspirin-intolerant asthma; ATA, aspirin-tolerant asthma; HWE, Hardy-Weinberg Equilibrium;
OR, odds ratio; CI, confidence interval; P ^cor., corrected P-value.

ISSN: 1471-2466