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Table 3 Association analysis between SNPs of FSIP1 gene and the fall of FEV1 by aspirin provocation.

From: Positive Association between Aspirin-Intolerant Asthma and Genetic Polymorphisms of FSIP1: a Case-Case Study

rs#

C/C

C/R

R/R

P*

 

n

Fall rate

n

Fall rate

n

Fall rate

 

rs1602543

356

9.74 ± 13.12

205

8.25 ± 13.03

31

9.88 ± 15.55

0.43

rs7179742

300

8.29 ± 12.05

241

9.49 ± 14.15

51

13.54 ± 14.55

0.01

rs1021411

335

8.84 ± 12.89

223

9.58 ± 13.87

34

10.88 ± 12.14

0.26

rs1021410

299

8.30 ± 12.03

245

9.56 ± 14.13

48

13.38 ± 14.86

0.01

rs12440567

322

8.36 ± 12.33

227

9.81 ± 14.15

43

12.76 ± 14.11

0.02

rs2576932

157

11.33 ± 15.8

290

8.34 ± 11.80

144

8.76 ± 12.69

0.06

rs10520151

564

9.15 ± 13.02

27

0.71 ± 17.32

1

13.8

0.50

rs16969802

324

8.38 ± 12.32

225

9.80 ± 14.18

43

12.68 ± 14.14

0.02

rs12911842

341

9.57 ± 13.93

210

9.30 ± 12.54

41

6.09 ± 9.94

0.14

rs7179417

156

11.40 ± 15.8

291

8.25 ± 11.78

145

8.87 ± 12.64

0.06

rs4115216

155

11.46 ± 15.8

292

8.23 ± 11.77

145

8.87 ± 12.64

0.06

rs8033957

162

9.08 ± 13.21

284

8.22 ± 11.59

145

11.41 ± 15.8

0.10

rs6492915

162

9.08 ± 13.21

284

8.22 ± 11.59

145

11.41 ± 15.8

0.10

rs8031241

153

11.52 ± 15.9

291

8.20 ± 11.76

147

8.91 ± 12.62

0.06

rs1906164

339

9.25 ± 12.60

216

9.21 ± 13.94

37

9.24 ± 14.74

0.98

  1. *P-values of regression analysis represent the co-dominant model controlling sex, smoking status, and atopy as covariates.
  2. C/C, C/R and R/R indicate the homozygote of common allele, and the heterozygote and homozygote of rare allele, respectively.
  3. Fall rate values are mean ± standard deviation.