Positive Association between Aspirin-Intolerant Asthma and Genetic Polymorphisms of FSIP1: a Case-Case Study

BMC Pulmonary Medicine

Table 4 Logistic and statistical analyses of FSIP1 haplotypes.

Haplotypes	MAF			Heterozygosity	HWE	OR (95%CI)	P	P ^cor.
	AIA	ATA	Total
FSIP1-_ BL1_ht1	0.235	0.256	0.254	0.379	0.770	0.91 (0.67-1.23)	0.52	1.00
FSIP1-_BL1_ ht2	0.202	0.241	0.227	0.351	0.683	0.76 (0.55-1.03)	0.08	1.00
FSIP1-_BL1_ ht3	0.187	0.214	0.208	0.330	0.498	0.85 (0.62-1.16)	0.30	1.00
FSIP1-_BL1_ ht4	0.244	0.190	0.202	0.322	0.546	1.42 (1.04-1.94)	0.03	1.00
FSIP1-_BL2_ ht1	0.262	0.302	0.295	0.416	0.614	0.82 (0.62-1.09)	0.18	1.00
FSIP1-_BL2_ ht2	0.199	0.226	0.214	0.336	0.207	0.82 (0.60-1.11)	0.20	1.00
FSIP1-_BL2_ ht3	0.130	0.148	0.146	0.250	0.400	0.88 (0.61-1.27)	0.49	1.00
FSIP1-_BL2_ ht4	0.151	0.098	0.111	0.197	0.908	1.61 (1.10-2.37)	0.02	0.76
FSIP1-_BL2_ ht5	0.123	0.104	0.109	0.195	0.839	1.34 (0.89-2.01)	0.17	1.00
FSIP1-_BL3_ ht1	0.238	0.291	0.283	0.406	0.011	0.78 (0.59-1.04)	0.09	1.00
FSIP1-_BL3_ ht2	0.298	0.269	0.278	0.401	0.600	1.21 (0.91-1.60)	0.19	1.00
FSIP1-_BL3_ ht3	0.157	0.202	0.187	0.304	0.575	0.70 (0.50-0.98)	0.04	1.00
FSIP1-_BL3_ ht4	0.117	0.072	0.085	0.155	0.200	1.76 (1.13-2.74)	0.01	0.66

MAF, minor allele frequency; AIA, aspirin intolerant asthma; ATA, aspirin tolerant asthma; HWE, Hardy-Weinberg equilibrium number; OR, odd ratio; CI, confidence interval; P ^cor., corrected P-value.

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