Table 3 Associations between MBC test outcome and constitutional, behavioural characteristics and markers of airway responsiveness and inflammation (percentage in column (n)) (N = 341).
MBC- FEV1's fall <20% (N = 322) | MBC FEV1's fall ≥20% (N = 19) | p | |
|---|---|---|---|
Constitutional characteristics | |||
Gender: Male | 56.2% (181) | 52.6% (10) | 0.76 |
Atopy in family* | 37.6% (121) | 52.6% (10) | 0.19 |
Clinical atopy† | 19.9% (64) | 10.5% (2) | 0.55** |
Personal atopy‡ (61 missing data) | 27.4% (72) | 64.7% (11) | <0.01** |
Behavioural characteristics | |||
Training track | |||
Bakery | 36.3% (117) | 26.3% (5) | |
Pastry making | 25.5% (82) | 26.3% (5) | 0.69** |
Hairdressing | 38.2% (123) | 47.4% (9) | |
Tobacco usage status | |||
Non smoker | 49.4% (159) | 42.1% (8) | |
Current smoker | 47.2% (152) | 52.6% (10) | 0.54** |
Past smoker | 3.4% (11) | 5.3% (1) | |
Baseline FEV1§ | |||
>80.8% | 86.3% (278) | 79.0% (15) | |
>76.0% and <80.7% | 8.7% (28) | 10.5% (2) | 0.31** |
<76.0% | 5.0% (16) | 10.5% (2) | |
Rrs4-16 increase post MBC test (%) (mean (sd)) | |||
<42.4% | 87.3% (281) | 84.2% (16) | |
>42.4% and <54.6% | 6.8% (22) | 10.5% (2) | 0.75** |
>54.6% | 5.9% (19) | 5.3% (1) | |
Clinical indicators of airway inflammation | |||
Rhinoconjunctivitis-like symptoms|| | 9.6% (31) | 5.3% (1) | 1.0** |
Asthma-like symptoms¶ | 4.0% (13) | 5.3% (1) | 0.56** |
Quantitative indicators of airway inflammation | |||
FENO in ppb (median (first-third quartiles) | 12.4 (8.9-17.6) | 16.4 (10.3-35.0) | 0.19†† |
FENO in percent predicted according to Travers# | |||
<140% | 87.3% (281) | 73.7% (14) | |
>140% and <225% | 7.1% (23) | 10.5% (2) | 0.09** |
>225% | 5.6% (18) | 15.8% (3) | |
Eosinophil count in nasal fluid lavage | |||
<1% | 86.7% (279) | 79.0% (15) | |
>1% and <14% | 6.5% (21) | 10.5% (2) | 0.37** |
>14% | 6.8% (22) | 10.5% (2) |