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Figure 2 | BMC Pulmonary Medicine

Figure 2

From: Insulin modulates cytokine release and selectin expression in the early phase of allergic airway inflammation in diabetic rats

Figure 2

Quantitative evaluation of the immune staining for E- and P- selectins on lung microvessels of ovalbumin (OA) sensitized non-diabetic and diabetic rats 6 hours after OA (experimental) or saline (control) instillation. Insulin (NPH, 4 IU/rat s.c.) was given to diabetic rats 2 hours before OA challenge. Values are means ± SEM for 8 samples/rat, 3 animals/group. Analyses were performed by using the software image-pro Plus, version 4.1, Media Cybernetics. *P < 0.001 comparing OA challenged with the control in the corresponding group (diabetic or non-diabetic). P < 0.0001 comparing diabetic rats treated vs non-treated with insulin. P < 0.001 comparing OA challenged with the diabetic or non-diabetic group.

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