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Table 1 General characteristics of the animals

From: Insulin modulates cytokine release and selectin expression in the early phase of allergic airway inflammation in diabetic rats

Groups

Body weight gain (g)

Blood glucose (mg/dL)

Control

147 ± 12

87 ± 2

Diabetic

11 ± 11*

531 ± 26*

Diabetic + insulin

13 ± 12 *

257 ± 15 *†

  1. Rats were rendered diabetic by the injection of alloxan (42 mg/Kg, i.v.), and measurement of body weight was carried out 24 days afterwards. Rats were immunized with OA and blood glucose levels in the 3 groups were determined 6 hours after antigen challenge. Insulin (NPH, 4 IU/rat, s.c.) was administered 2 hours before the intratracheal instillation procedure.Values are means ± SEM. The number of animals in each group was 9. *P < 0.001 comparing diabetic with control (non-diabetic) rats. † P < 0.001 comparing insulin-treated vs non-treated diabetic rats.
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BMC Pulmonary Medicine

ISSN: 1471-2466

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