|
prior n° of exac.
|
prior number (n°) of hospitalisations
|
|---|
| |
0
|
1
|
2
|
|---|
| |
IC
|
IE
|
ICER
|
IC
|
IE
|
ICER*
|
IC
|
IE
|
ICER*
|
|---|
|
0
|
428
|
0.0000
|
dominated
|
84
|
0.0008
|
107666
|
-259
|
0.0016
|
cost saving
|
| |
426
|
429
|
0.0000
|
0.0000
| |
-581
|
819
|
-0.0009
|
0.0027
| |
-1589
|
1211
|
-0.0017
|
0.0054
| |
|
1
|
420
|
0.0005
|
1265951
|
77
|
0.0012
|
62094
|
-266
|
0.0020
|
cost saving
|
| |
416
|
424
|
0.0001
|
0.0008
|
497057
|
4154369
|
-590
|
812
|
-0.0004
|
0.0033
| |
-1599
|
1204
|
-0.0013
|
0.0061
| |
|
2
|
413
|
0.0009
|
622357
|
70
|
0.0017
|
41019
|
-274
|
0.0025
|
cost saving
|
| |
406
|
419
|
0.0002
|
0.0017
|
242740
|
2049176
|
-599
|
805
|
0.0000
|
0.0039
| |
-1608
|
1196
|
-0.0008
|
0.0066
| |
|
3
|
405
|
0.0014
|
407826
|
62
|
0.0022
|
28873
|
-281
|
0.0029
|
cost saving
|
| |
395
|
415
|
0.0003
|
0.0025
|
158255
|
1338516
|
-608
|
797
|
0.0002
|
0.0046
| |
-1617
|
1189
|
-0.0003
|
0.0072
| |
|
4
|
398
|
0.0018
|
300561
|
55
|
0.0026
|
20974
|
-289
|
0.0034
|
cost saving
|
| |
384
|
410
|
0.0004
|
0.0034
|
116258
|
983186
|
-618
|
790
|
0.0003
|
0.0053
| |
-1626
|
1182
|
0.0000
|
0.0077
| |
|
5
|
391
|
0.0023
|
236201
|
47
|
0.0031
|
15425
|
-296
|
0.0038
|
cost saving
|
| |
374
|
406
|
0.0005
|
0.0042
|
90683
|
769988
|
-627
|
780
|
0.0005
|
0.0061
| |
-1635
|
1175
|
0.0003
|
0.0085
| |
|
6
|
383
|
0.0027
|
193295
|
40
|
0.0035
|
11314
|
-303
|
0.0043
|
cost saving
|
| |
363
|
401
|
0.0006
|
0.0050
|
74097
|
627857
|
-634
|
770
|
0.0007
|
0.0068
| |
-1645
|
1167
|
0.0004
|
0.0092
| |
|
7
|
376
|
0.0032
|
162648
|
32
|
0.0040
|
8146
|
-311
|
0.0048
|
cost saving
|
| |
352
|
397
|
0.0007
|
0.0059
|
62023
|
529076
|
-641
|
760
|
0.0008
|
0.0076
| |
-1654
|
1160
|
0.0006
|
0.0099
| |
|
8
|
368
|
0.0036
|
139662
|
25
|
0.0044
|
5630
|
-318
|
0.0052
|
cost saving
|
| |
341
|
392
|
0.0008
|
0.0067
|
52879
|
456718
|
-650
|
750
|
0.0010
|
0.0084
| |
-1663
|
1153
|
0.0007
|
0.0106
| |
|
9
|
361
|
0.0041
|
121784
|
18
|
0.0049
|
3583
|
-326
|
0.0057
|
cost saving
|
| |
330
|
388
|
0.0009
|
0.0075
|
45609
|
400440
|
-659
|
740
|
0.0011
|
0.0092
| |
-1672
|
1143
|
0.0008
|
0.0114
| |
|
10
|
353
|
0.0046
|
107482
|
10
|
0.0053
|
1885
|
-333
|
0.0061
|
cost saving
|
| |
319
|
383
|
0.0010
|
0.0084
|
39741
|
355417
|
-667
|
730
|
0.0012
|
0.0100
| |
-1681
|
1133
|
0.0010
|
0.0122
| |
- Exac. = exacerbations
- IC: incremental cost (expressed in euro); IE: incremental effect (expressed in quality-adjusted life years (QALY) gained); ICER: incremental cost-effectiveness ratio (expressed in cost per QALY gained). In every cell, the mean value and the lower (2.5%) and upper (97.5%) limits of the interval are mentioned.
- * the ICERs of the probabilistic model are not mentioned since simulation results are spread over several quadrants of the cost-effectiveness plane. As an alternative (in italics), the ICER calculated by dividing the mean incremental cost by the mean incremental benefit is presented.
