Progressive Group | Non-Progressive Group | ||
---|---|---|---|
Patients, n | 49 | 72 | |
Age, y (range) | 70.51 ± 9.3 | 69.95 ± 8.9 | |
Gender, F/M (%) | 12/37 (24.5/75.5) | 26/46 (36.1/63.9) | |
FcγRIIa Genotypes, n (%) | RR | 16 (32.7) | 32 (44.4) |
RH | 19 (38.8) | 32 (44.4) | |
HH | 14 (28.6) | 8 (11.1) | |
χ2 = 6.13, df2, p = 0.047 | |||
FcγRIIa Alleles, n (%) | R | 51 (52.0) | 96 (66.7) |
H | 47 (48.0) | 48 (33.3) | |
p = 0.023, OR 1.84, 95% CI 1.09-3.12 | |||
FEV 1 , L (% predicted) | 2.29 ± 0.6 (90.3 ± 20.9) | 2.19 ± 0.6 (89.2 ± 18.8) | |
FVC, L (% predicted) | 2.81 ± 0.7 (86.8 ± 21.1) | 2.86 ± 0.8 (91.7 ± 17.8) | |
FEV 1 /VC, % predicted | 81.96 ± 9.9 | 77.05 ± 9.5 | |
TLC, L (% predicted) | 4.33 ± 1.0 (71.5 ± 15.6) | 4.43 ± 1.0 (76.8 ± 13.5) | |
D L CO , ml/min/mmHg (% predicted) | 4.13 ± 1.3 (52.2 ± 16.3) | 4.18 ± 1.3 (53.8 ± 14.3) | |
K CO , ml/min/mmHg/L (% predicted) | 1.08 ± 0.3 (82.7 ± 22.8) | 1.10 ± 0.3 (81.7 ± 22.8) |