Table 2 Characteristics of subjects included in breath sampling
| Â | Healthy controls | CF - Ps. aeruginosacolonised | CF - Ps. aeruginosanon-colonised |
|---|---|---|---|
Number (n) | 17 | 16 | 13 |
Age years (mean range) | 38 (25-54) | 26.9 (13-59) | 14.9 (6-43) |
Male (%) | 38% | 63% | 53% |
BMI (kg/m2) (mean range) | Â | 19.07 (17.1-24.4) | 19.9 (14.8-37.2) |
Respiratory function: FEV1% | Â | 44.92 (13-93) | 77.15 (48-99) |
FVC% | Â | 59.51 (1.14-102) | 91.1 (55-120) |
Genetic analysis | Â | Sweat test (3) | Sweat test (3) |
|  |  | ΔF508/ΔF508 (9) | ΔF508/ΔF508 (5) |
|  |  | ΔF508/G542X (3) | ΔF508/G542X (1) |
|  |  | ΔF508/c.1339delA (1) | c.F508/c.1766+1g (1) |
|  |  |  | ΔF508/3849+10kbct (1) |
| Â | Â | Â | c.1624g > t(p.g542x)/c.1 |
| Â | Â | Â | 624g > t(p.g542x) (1) |
|  |  |  | ΔF508/P67L (1) |
Diagnoses ^ | Â | Â | Â |
Pancreatic insufficiency | Â | 15 | 12 |
Chronic rhinosinuitis | Â | 9 | 0 |
Osteopenia | Â | 8 | 0 |
Gastro-oesophageal disease | Â | 7 | 0 |
CF related diabetes | Â | 4 | 3 |
Vitamin A, D & E deficiency | Â | 5 | 1 |
Asthma | Â | 5 | 0 |
Allergic bronchopulmonary | Â | 0 | 3 |
aspergillosis | Â | Â | Â |
Distal intestinal obstruction | Â | 1 | 2 |
syndrome | Â | Â | Â |
Previous tuberculosis | Â | 1 | 0 |
Pancreatitis | Â | 1 | 0 |
Chronic nasal polyps | Â | 0 | 1 |
Haemoptysis | Â | 0 | 0 |
Chronic eczema & ichthyosis | Â | 1 | 1 |