Figure 1
From: Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice
Serum levels of ECM specific antibodies. Serum levels of IgM (A,B), and IgG1 and IgG2a (C) antibodies against decorin, collagen and elastin are depicted. In A) the levels of the ECM specific antibodies are shown for the 3 months exposed mice. In B) and C) the levels of ECM specific antibodies are shown for the 6 months exposed mice. Below the figures the different exposures are indicated; Control = control immunization with adjuvant, ECM = immunization with ECM proteins, Smoke = smoke exposure, Sham smoke = control exposure to air. Smoke exposed mice are indicated with black symbols and sham smoke exposed mice with open symbols. * indicates p < 0.05.