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Table 3 Analysis of effectiveness of each screening strategy

From: Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis

Effectiveness Measures TST T-SPOT.TB QFT-GIT TST/T-SPOT.TB TST/QFT-GIT
Numbers of post-primary TB cases in 2 year period 4.52 3.80 4.03 4.67 4.85
Number of TB cases prevented by screening strategy 2.98 3.70 3.47 2.83 2.65
Numbers of people treated for LTBI 284 228 242 174 168
Numbers of true positives treated 184 228 214 174 163
Numbers of false positives treated 101 0 28 0 5
Numbers of people treated for LTBI per case of active TB prevented (NNT) 95.5 61.7 69.7 61.7 63.6
  1. Effectiveness measures relate to outcomes and costs for entire cohort of 1,000 contacts over the 2 year examination period. No screening results in 7.5 cases of post-primary TB in the 2 year period. (TST - Tuberculin Skin Test, QFT-GIT - Quantiferon-TB Gold-In-Tube, NNT- number needed to treat)