Figure 7

S100A7/psoriasin mRNA expression is elevated upon pathogen exposure in BAL fluid cells. S100A7/psoriasin mRNA expression level was compared on the basis of pathogen detection and independent of the COPD status. S100A7/psoriasin mRNA expression (A) in bronchial biopsies without (negative, N = 19) or with detection of pathogens (positive, N = 20); (B) in BAL fluid cells without (negative, N = 8) and with detection of pathogens (positive, N = 23); (C) in BAL fluid cells negative for a pathogen (N = 8) and positive for E. coli (N = 5) and S. aureus (N = 5). Differences between the groups were analyzed by unpaired t-test from log transformed data with p < 0.05 considered as significant.