Characteristic | Healthy controls | COPD patients | |||
---|---|---|---|---|---|
 |  | Stage 1 | Stage 2 | Stage 3 | Stage 4 |
Number | 10 | 2 | 13 | 15 | 4 |
Age [years] | 31.3 ± 7.8 (20-46) | 73.5 ± 7.8 (68-79) | 66.9 ± 9.9 (52-82) | 66.4 ± 7.5 (46-77) | 58.3 ± 3.6 (55-63) |
Sex [M/F] | 3/7 | 1/1 | 9/4 | 10/5 | 2/2 |
BMI | 22.7 ± 1.9 (20.0-26.7) | 27.2 ± 0.2 (27.0-27.3) | 28.3-5.8 (22.5-44.6) | 25.4 ± 4.7 (16.0-35.5) | 21.3 ± 3.7 (16.2-24.5) |
Pack years | 2.9 ± 2.8 (1-7) | 50.0 ± 14.1 (40-60) | 41.9 ± 19.3 (10-85) | 39.7 ± 16.6 (5-65) | 42.5 ± 18.9 (30-70) |
6MWD [m] | 516.0 ± 49.3 (430-625) | 305.0 ± 169.7 (185-425) | 352.3 ± 127.1 (150-545) | 291.0 ± 122.3 (0-465) | 367.5 ± 88.6 (240-430) |
FEV1 [%] | 104.2 ± 16.6 (60.7-117.4) | 89.9 ± 2.0 (88.5-91.3) | 63.9 ± 10.2 (50.1-79.4) | 38.2 ± 6.2 (30.2-47.3) | 26.1 ± 2.8 (22.8-29.0) |
VC [%] | 108.5-26.4 (54.4-160.9) | 107.3 ± 2.3 (105.7-108.9) | 86.3 ± 12.4 (65.2-108.9) | 69.2 ± 14.7 (42.6-97.7) | 61.3 ± 10.6 (52.8-76.3) |
FEV1/VC [%] | 88.7 ± 8.6 (73.5-101.5) | 73.1 ± 11.2 (65.2-81.0) | 65.6 ± 12.6 (49.5-90.7) | 46.8 ± 10.3 (30.0-66.3) | 39.1 ± 7.5 (31.5-46.3) |
BODE score | †| 2.0 ± 2.8 (0.0-4.0) | 2.2 ± 2.3 (0.0-6.0) | 5.1 ± 2.1 (2.0-9.0) | 6.3 ± 1.0 (5.0-7.0) |