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Table 2 Characteristics of the subjects in the induced sputum analyses

From: Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma

Variable

Middle aged/elderly

  
 

Non-smokers

Smokers

COPD

Subjects, n

15

20

19

Age, yr

52 ± 1.9

52 ± 1.5

61 ± 1.9***

Sex, M/F

5/10

13/7

17/2**

Pack years, yr

0

29 ± 1.9***

45 ± 3.8***

Post-bronchodilator

   

   FVC, l

3.9 ± 0.21

4.2 ± 0.19

3.6 ± 0.15

   FEV1, l

3.3 ± 0.15

3.5 ± 0.13

2.1 ± 0.13***

   FEV1, % predicted

107 ± 3.9

100 ± 1.7

64 ± 3.2***

   FEV1/FVC

86 ± 1.4

83 ± 1.0

59 ± 2.7***

  1. Data are shown as mean ± SEM
  2. COPD, chronic obstructive pulmonary disease; FVC, Forced vital capacity; FEV1, Forced expiratory volume in one second
  3. *p < 0.05; **p < 0.01; ***p < 0.001 (vs middle aged/elderly non-smokers, Mann-Whitney U test or Chi-square test)