From: Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma
Variable | Middle aged/elderly | Â | Â |
---|---|---|---|
 | Non-smokers | Smokers | COPD |
Subjects, n | 15 | 20 | 19 |
Age, yr | 52 ± 1.9 | 52 ± 1.5 | 61 ± 1.9*** |
Sex, M/F | 5/10 | 13/7 | 17/2** |
Pack years, yr | 0 | 29 ± 1.9*** | 45 ± 3.8*** |
Post-bronchodilator | Â | Â | Â |
   FVC, l | 3.9 ± 0.21 | 4.2 ± 0.19 | 3.6 ± 0.15 |
   FEV1, l | 3.3 ± 0.15 | 3.5 ± 0.13 | 2.1 ± 0.13*** |
   FEV1, % predicted | 107 ± 3.9 | 100 ± 1.7 | 64 ± 3.2*** |
   FEV1/FVC | 86 ± 1.4 | 83 ± 1.0 | 59 ± 2.7*** |