From: Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma
 | Non-smokers | Smokers | COPD |
---|---|---|---|
Subjects, n | 7 | 7 | 14 |
Age, yr | 65 ± 3.1 | 62 ± 2.6 | 60 ± 2.1 |
Sex, M/F | 3/4 | 6/1 | 9/4 |
Pack years, yr | - †| 24 ± 5.7 | 37 ± 3.8 |
Post-bronchodilator | Â | Â | Â |
   FVC, l | 4.5 ± 0.56 | 3.7 ± 0.25 | 2.4 ± 0.31** |
   FEV1, l | 3.5 ± 0.47 | 3.1 ± 0.19 | 1.2 ± 0.24** |
   FEV1, % predicted | 106 ± 4.6 | 88 ± 3.5* | 34 ± 6.1*** |
   FEV1/FVC | 79 ± 2.8 | 82 ± 2.3 | 45 ± 5.3** |