Fluticasone/formoterol combination therapy is as effective as fluticasone/salmeterol in the treatment of asthma, but has a more rapid onset of action: an open-label, randomized study

Table 2 Change in FEV₁ assessments from baseline to week 12

Parameter	Change from baseline (L) LS mean (95% CI)	Difference between groups (L) LS mean (95% CI)	pvalue for non-inferiority
Pre-dose FEV ₁
Fluticasone/formoterol	0.196 (0.117, 0.275)	–0.061 (–0.161, 0.040)	0.007
Fluticasone/salmeterol	0.257 (0.177, 0.336)
Post-dose FEV ₁
Fluticasone/formoterol	0.464 (0.374, 0.555)	–0.013 (–0.129, 0.103)	0.002
Fluticasone/salmeterol	0.477 (0.384, 0.569)

ISSN: 1471-2466