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Table 1 Haemodynamic and prognostic data

From: Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?

  Time of presentation (/w dasatinib) Time course under sildenafil (w/o dasatinib)
Month: 0 +1 + 3 + 5 + 7
RVSP [mm Hg] 73 51 - 17 -
PAP mean [mm Hg] 52 - - - 40
PVR [dyn*s/cm -5 ] 1250 - - - 356
CO [l/min] 1.7 - - - 4.7
HR [/min] 105 - - - 85
proBNP [ng/l] 27055 3037 1334 2076 -
6MWD [m] 0 308 458 - -
WHO/NYHA FC IV II I/II II II
  1. RVSP: right ventricular systolic pressure; PAPmean: mean pulmonary artery pressure; PVR: pulmonary vascular resistance; CO: cardiac output; HR: heart rate; proBNP: brain natriuretic peptide propeptide; 6MWD: 6-minute walk distance; WHO/NYHA FC: World Health Organization/New York Heart Association functional class