Table 2 Established end-points of bleomycin-induced lung injury and fibrosis in mice that did or did not undergo lung function measurements.
From: Static and dynamic mechanics of the murine lung after intratracheal bleomycin
| Â | day 7 | day 21 | ||
|---|---|---|---|---|
| Â | C57BL/6 | Balb/c | C57BL/6 | Balb/c |
no lung function measurements performed | ||||
n | 3 | 3 | 4 | 0 |
lung injury score | 2.8 ± .5 | 3.0 ± .0 | 3.8 ± .8 | - |
TVD (%) | 30.5 ± .2 | 26.5 ± 7.4 | 30.3 ± 3.4 | - |
lung collagen (μg) | 205 ± 99 | 185 ± 92 | 320 ± 230 | - |
lung function measurements performed | ||||
n | 8 | 5 | 7 | 9 |
lung injury score | 2.8 ± 1.7 | 3.4 ± 0.4 | 3.6 ± .5 | 1.3 ± 1.5 |
TVD (%) | 29.5 ± 9.6 | 23.7 ± 6.5 | 31.5 ± 3.4 | 24.3 ± 6.3 |
lung collagen (μg) | 211 ± 102 | 177 ± 101 | 325 ± 312 | 179 ± 69 |