Table 3 Effects of tachykinins receptors NK1, NK2 AND NK3 on human airway cells
From: Tachykinin receptors antagonism for asthma: a systematic review
Receptors | |||
|---|---|---|---|
Effect on human airway cells | NK1 | NK2 | NK3 |
Chemotaxis | +++ | - | - |
Lymphocyte proliferation | +++ | + | - |
Increased neutrophil motility | +++ | + | - |
Monocyte/macrophage stimulation | ++ | + | - |
Mast cell activation | ++ | + | - |