Elevated placenta growth factor predicts pneumonia in patients with chronic obstructive pulmonary disease under inhaled corticosteroids therapy

Table 1 Demographic characteristics of the patients with COPD

Variables	COPD with ICS	COPD without ICS	pvalue
	(n = 125)	(n = 149)
Age	66.7 ± 24.8	69.1 ± 25.1	0.62
Gender (M/F)	117/8	136/13	0.68
smoking (pack-years)	25.3 ± 14.2	22.1 ± 11.9	0.49
Lung function
mild obstruction	0	47 (31.5%)	< 0.01*
moderate obstruction	41 (32.8%)	77 (51.7%)	0.04*
severe obstruction	54 (43.2%)	17 (11.4%)	< 0.01*
very severe obstruction	30 (24%)	8 (5.4%)	< 0.01*
Pneumonia	20 (16%)	9 (6%)	0.02*
C-reactive Protein (CRP) (mg/L)	4.8 ± 1.9	4.3 ± 2.2	0.45
Placenta Growth Factor (PlGF)(pg/L)	53.5 ± 18	37.6 ± 18.3	< 0.01*

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