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Table 2 Characteristics of the patients with each sign of pulmonary venous obstruction

From: Pulmonary venous occlusion and death in pulmonary arterial hypertension: survival analyses using radiographic surrogates

Signs

Cause

n

Age(years)

mRAP(mm Hg)§

mPAP (mm Hg)§

CI(L/min/m2)

BNP(pg/mL)

Mediastinal

Yes

Idiopathic

6

56 ± 18*,#

9 ± 4

43 ± 5

1.9 ± 0.4

860 [637 - 1210]**

adenopathy

 

CTD

3

65 ± 3*,#

8 ± 3

36 ± 19

2.5 ± 0.3

148 [83 - 959]**

 

No

Idiopathic

12

37 ± 17*,#

8 ± 3

62 ± 16

2.4 ± 0.7

133 [37 - 418]**

  

CTD

16

52 ± 16*,#

7 ± 4

48 ± 19

2.5 ± 0.9

141 [75 - 334]**

Thickening of

Yes

Idiopathic

8

50 ± 19

9 ± 5

56 ± 16

1.9 ± 0.4*

800 [487-1062]*

interlobular septa

 

CTD

6

49 ± 18

7 ± 4

42 ± 18

2.0 ± 0.4*

482 [83-959]*

 

No

Idiopathic

10

38 ± 19

7 ± 2

56 ± 16

2.5 ± 0.7*

92 [28 - 333] *

  

CTD

13

56 ± 14

7 ± 3

42 ± 18

2.7 ± 0.9*

126 [34 - 290]*

Centrilobular

Yes

Idiopathic

4

39 ± 20

9 ± 5

56 ± 16

2.1 ± 0.5

487 [236 - 715]

ground-glass

 

CTD

5

54 ± 24

9 ± 4

49 ± 15

2.0 ± 0.5

148 [141 - 959]

attenuation

No

Idiopathic

14

45 ± 19

8 ± 3

61 ± 18

2.3 ± 0.7

263 [46 - 806]

  

CTD

14

55 ± 13

6 ± 3

45 ± 20

2.7 ± 0.9

111 [34 - 334]

  1. Values are number (percent) or mean ± SD, as appropriate. Data of BNP are shown as median [25percentile, 75percentile]. P values for the comparison between the patients with and without each radiographic surrogate for obstruction of the pulmonary veins; *: < 0.02 and **: < 0.01. P values for the comparison for the difference between the causes; # : < 0.03. No mark means that there is no significant effect of either the presence and absence of each radiographic surrogate or the difference in the cause. §: The values for mRAP and mPAP are based on 26 patients. BNP = brain natriuretic peptide, CI = cardiac index, CTD = connective tissue disorder, mRAP = mean right atrial pressure, mPAP = mean pulmonary arterial pressure, RV = right ventricle, SD = standard deviation.