From: Asthma control cost-utility randomized trial evaluation (ACCURATE): the goals of asthma treatment
 | Levels of asthma control |  | |
---|---|---|---|
Strategy | Strictly controlled | Sufficiently controlled | Uncontrolled |
STRICT-strategy | - 3 mo: no change | step-up: treatment choice | step-up: treatment choice |
 | - > 3 mo: step-down |  |  |
SUFF-strategy | step-down | no change | step-up: treatment choice |
FeNO strategy | Â | Â | Â |
- Low FeNO level | step-down | - 3 mo: no change/change within current step to LABA | step-up: LABA |
 |  | - > 3 mo: step-down ICS |  |
- Intermediate FeNO level | no change | step-up: treatment choice | step-up: treatment choice |
- High FeNO level | step-up/change within current step to ICS | step-up: 1 × ICS | step-up: 2 × ICS* |