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Table 3 Inhaled Corticosteroids (ICS) and the Risk of Herpes Zoster Among Cases and Controls Treated with Inhibitors of Cytochrome Oxidase P450 3A4*

From: Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study

  Cases (n = 475) Controls (n = 760) Crude Odds Ratio Adjusted Odds Ratio† (95% CI ‡)
ICS     
no use% 35.6 36.1 1.0 reference
high dose% 24.4 20.8 1.13 1.24 (0.81-1.90)
medium dose% 16.8 18.2 0.95 0.94 (0.63-1.41)
low dose% 2.5 3.3 0.75 0.66 (0.29-1.48)
  1. *see list of inhibitors of cytochrome P450 3A4 in methods.
  2. †Adjusted for gender, smoking status, all the variables in Table 1, as well as past use of ICS.
  3. ‡CI: confidence interval