Table 2 Efficacy endpoints: FENO, PC20 AMP, and FEV1.
FENO (ppb) - Day 3, 4 hours | LS Mean | 95% CI |
|---|---|---|
High dose | 50.5 | 43.8, 57.3 |
Low dose | 58.9 | 52.2, 65.7 |
Placebo | 71.1 | 64.4, 77.8 |
FE NO (ppb) - Day 3, 2 hours | LS Mean | 95% CI |
High dose | 51.8 | 44.5, 59.2 |
Low dose | 60.2 | 53.0, 67.5 |
Placebo | 74.4 | 67.2, 81.5 |
AMP PC 20 (mg/mL) - Day 3, 4 hours | Log2 LS Mean | Log2 95% CI |
High dose | 7.1 | 5.9, 8.2 |
Low dose | 6.0 | 4.9, 7.1 |
Placebo | 2.3 | 1.2, 3.4 |
FEV 1 (L) - AUC 0-4 h Day 1 | LS Mean | 95% CI |
High dose | 3.6 | 3.5, 3.6 |
Low dose | 3.6 | 3.5, 3.6 |
Placebo | 3.4 | 3.3, 3.4 |