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Table 5 Unadjusted associations between maternal factors and prenatal exposures on the risk of wheezing

From: Particular characteristics of allergic symptoms in tropical environments: follow up to 24 months in the FRAAT birth cohort study

 

6 months

7 - 12 months

0 - 24 months

Factor/exposure

Wheezing ever

(n = 50/236)

Wheezing ever

(n = 59/221)

Wheezing ever*

(n = 105/169)

Recurrent wheezing*

(n = 39/235)

 

OR (95%CI)

P value

OR (95%CI)

P value

OR (95%CI)

P value

OR (95%CI)

P value

Maternal asthma

1.19 (0.38-3.74)

0.76

2.73 (1.06-7.03)

0.03†

2.35 (0.91-6.06)

0.069

3.10 (1.10-8.73)

0.025¶

Maternal rhinitis

2.80 (1.50-5.24)

0.001 ‡

1.14 (0.61-2.11)

0.67

1.73 (1.02-2.93)

0.041

1.78 (0.88-3.58)

0.10

Mother education

        

< 5

0.81 (0.33-1.98)

0.65

0.76 (0.31-1.85)

0.54

0.99 (0.48-2.01)

0.98

0.92 (0.33-2.55)

0.88

> 11

1.22 (0.50-2.99)

0.65

1.31 (0.54-3.19)

0.54

1.00 (0.49-2.05)

0.98

1.07 (0.39-2.97)

0.88

Parity

        

Primiparous

0.96 (0.52-1.79)

0.91

1.03 (0.57-1.84)

0.91

0.84 (0.51-1.38)

0.49

0.97 (0.48-1.93)

0.93

Type of house

        

   Wood

0.60 (0.27-1.31)

0.20

0.89 (0.45-1.75)

0.74

0.99 (0.56-1.74)

0.98

0.40 (0.15-1.07)

0.069

Type of floor

        

   Soil

0.94 (0.37-2.36)

0.90

0.73 (0.31-1.73)

0.48

1.00 (0.48-2.09)

0.98

0.76 (0.28-2.07)

0.59

Tap water

        

   No

0.64 (0.21-1.93)

0.43

0.35 (0.10-1.20)

0.09

0.70 (0.31-1.55)

0.38

0.59 (0.17-2.04)

0.40

Sewage

        

   No

1.05 (0.56-1.96)

0.86

0.87 (0.48-1.58)

0.66

1.07 (0.65-1.75)

0.78

0.60 (0.29-1.24)

0.16

Socioeconomic strata

        

   1 (poorest)

1.10 (0.51-2.35)

0.80

0.59 (0.31-1.14)

0.12

0.76 (0.42-1.36)

0.36

0.92 (0.41-2.07)

0.84

Prenatal exposure to cigarette smoke

        

   Yes

1.43 (0.77-2.64)

0.24

0.99 (0.55-1.77)

0.98

1.28 (0.78-2.09)

0.32

0.95 (0.48-1.90)

0.89

Exposure to fume wood/coal

        

   Yes

0.42 (0.12-1.43)

0.16

1.23 (0.52-2.88)

0.63

1.11 (0.52-2.36)

0.77

1.46 (0.55-3.81)

0.43

Exposure to fume trash burning:

        

at home

0.95 (0.44-2.04)

0.90

0.87 (0.42-1.81)

0.71

1.05 (0.57-1.92)

0.86

0.67 (0.26-1.69)

0.40

at neighborhood

1.33 (0.71-2.47)

0.36

1.08 (0.61-1.93)

0.77

1.22 (0.75-2.00)

0.41

1.62 (0.80-3.28)

0.17

Pets during pregnancy

        

Intradomicilliary (9 mo)

1.01 (0.55-1.87)

0.95

1.23 (0.67-2.23)

0.49

1.12 (0.67-1.88)

0.64

1.12 (0.55-2.28)

0.74

Intradomicilliary (ever)

1.09 (0.58-2.07)

0.77

0.92 (0.52-1.64)

0.79

1.04 (0.64-1.69)

0.87

0.99 (0.50-1.95)

0.98

Dog at home

0.97 (0.52-1.80)

0.93

0.91 (0.51-1.63)

0.77

1.00 (0.61-1.64)

0.98

0.80 (0.40-1.59)

0.53

Cat at home

0.93 (0.36-2.38)

0.89

0.78 (0.30-1.98)

0.60

0.66 (0.30-1.46)

0.31

0.81 (0.26-2.45)

0.71

Poultry/pigs at home

1.39 (0.62-3.15)

0.41

1.64 (0.76-3.55)

0.20

1.43 (0.71-2.89)

0.30

1.49 (0.60-3.68)

0.38

Rodents at home

0.84 (0.38-1.88)

0.68

1.24 (0.54-2.83)

0.60

1.52 (0.75-3.08)

0.23

0.82 (0.33-2.01)

0.67

Cockroaches at home

0.92 (0.44-1.94)

0.84

0.93 (0.46-1.86)

0.83

0.74 (0.41-1.35)

0.33

0.85 (0.38-1.92)

0.70

Gender

        

   Male

1.87 (0.99-3.51)

0.052 §

1.37 (0.76-2.45)

0.28

1.61 (0.98-2.64)

0.055

1.47 (0.74-2.93)

0.26

  1. *Cumulative prevalence
  2. †If the true odds ratio for disease in exposed subjects relative to unexposed subjects is (Ψ = 2.73), the test rejects the null hypothesis that this odds ration equals 1 with 0.56 power
  3. Maternal asthma "Yes" (5.4% in non-wheezers vs. 13.6% in wheezers)
  4. ¶ If the true odds ratio for disease in exposed subjects relative to unexposed subjects is (Ψ = 3.10), the test rejects the null hypothesis that this odds ration equals 1 with 0.55 power
  5. Maternal asthma "Yes" (5.5% in non-recurrent vs. 15.4% in recurrent wheezers)
  6. ‡If the true odds ratio for disease in exposed subjects relative to unexposed subjects is (Ψ = 2.8), the test rejects the null hypothesis that this odds ration equals 1 with 0.89 power
  7. Maternal rhinitis "Yes" (26.3 in non-wheezers vs. 50% in wheezers); (25.4% in non-wheezers vs. 37.1% in wheezers at 24 months)
  8. § If the true odds ratio for disease in exposed subjects relative to unexposed subjects is (Ψ = 1.87), the test rejects the null hypothesis that this odds ration equals 1 with 0.50 power
  9. Male gender "Yes" (48.7% in non-wheezers vs. 64% in wheezers)
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BMC Pulmonary Medicine

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