Figure 4

Modulation of chaperone levels in the cells expressing SP-C ^WT and SP- ^A116D by pharmacologic substances. Shown is the expression relative to β-actin of the chaperone proteins calnexin (A), calreticulin (B), Hsp70 (C) and Hsp90 (D) in MLE-12 cells expressing proSP-C^WT or proSP-C^A116D and either untreated (-) or exposed to cyclophosphamide (Cyc), azathioprine (Aza), methylprednisolone (Met), or hydroxychloroquine (Hyd). Only significant p-values are presented.