|
COPD GOLD stage
|
|---|
| |
Stage I(mild)
|
Stage II (moderate)
|
Stage III (severe)
|
Stage IV (very severe)
|
P-value
|
|
N
|
15
|
42
|
27
|
6
| |
|
Males (%)
|
86.7
|
86
|
96.3
|
100
|
0.41
|
|
Age (years)
|
68 (58–74)
|
67 (62–73)
|
68 (61–73)
|
63 (53–75)
|
0.78
|
|
Pack years
|
60 (42–75)
|
55 (34–81)
|
70 (40–92)
|
68 (50–151)
|
0.52
|
|
BMI (kg/m²)
|
27 (26–32)
|
29 (25–34)
|
26 (24–30)
|
25 (21–29)
|
0.12
|
|
Current smoking (%)
|
53.3
|
52.4
|
51.9
|
33.3
|
0.84
|
|
FEV1 (% predicted)
|
83 (81–86)
|
62 (56–70)
|
37 (33–44)
|
22 (20–27)
|
p < 0.01
|
|
6MWD (m)
|
450 (360–480)
|
420 (315–545)
|
360 (300–420)
|
375 (255–458)
|
0.07
|
|
MRC dyspnea grade
|
1 (1–2)
|
1 (1–2)
|
2 (1–3)
|
3 (2–4)
|
P < 0.01
|
|
BODE index quartile
| | | | | |
|
(n(%))
| | | | | |
|
1
|
15 (100.0)
|
40 (95.2)
|
8 (29.6)
|
1 (16.7)
| |
|
2
| |
1 (2.4)
|
14 (51.9)
|
1 (16.7)
| |
|
3
| |
1 (2.4)
|
4 (14.8)
|
3 (50.0)
| |
|
4
| | |
1 (3.7)
|
1 (16.7)
| |
- Data represent median (interquartile range). BMI = body mass index. Pack years: amount of cigarette packs smoked per day multiplied by the amount of years smoked. 6MWD = 6 Minute Walking Distance. MRC = Medical Research Council dyspnoea scale. BODE: body mass index, airflow limitation (forced expiratory volume in one second), dyspnoea and 6-min walk distance. FEV1 = Post-bronchodilator Forced Expiratory Volume in 1 s 20 min after inhaled bronchodilator. GOLD stages = COPD classification by post-bronchodilator spirometry according to GOLD guidelines.
