Table 2 Univariate cox regression model for time to hospital discharge
Parameters | HR (95%CI) | p |
|---|---|---|
Demographics | ||
Female Gender | 0.95 (0.83-1.08) | 0.41 |
Age (age <60 Reference group) | ||
Age 60–70 years | 0.63 (0.52-0.77) | <0.001 |
Age 70–80 years | 0.52 (0.43-0.63) | <0.001 |
Age >80 years | 0.46 (0.38-0.55) | <0.001 |
Past medical history | ||
Fever (Temp > 38.5°C) | 0.82 (0.71-0.95) | 0.01 |
Active smoker | 0.85 (0.73-0.98) | 0.03 |
Regular alcohol consumption | 1.15 (1.01-1.31) | 0.05 |
Clinical presentation | ||
BP systolic < 90 mmHg | 0.67 (0.44-0.99) | 0.05 |
BP diastolic < 60 mmHg | 0.77 (0.54-10.7) | 0.22 |
Pulse > 100 bpm | 0.93 (0.81-1.07) | 0.32 |
Temperature >38.5 or < 36°C | 1.01 (0.88-1.15) | 0.93 |
Respiratory rate > 20 bpm | 0.72 (0.62-0.82) | <0.001 |
Confusion | 0.76 (0.59-0.99) | 0.04 |
Situation at home | ||
Nursing home or needing regular nursing assistance at home | 0.70 (0.61-0.81) | <0.001 |
Comorbid condition | ||
Chronic pulmonary disease | 0.75 (0.65-0.86) | <0.001 |
Chronic heart failure | 0.68 (0.57-0.81) | <0.001 |
Diabetes | 0.8 (0.67-0.95) | <0.001 |
Tumor | 0.89 (0.73-1.09) | 0.22 |
Chronic renal failure | 0.73 (0.62-0.86) | <0.001 |
Type of medical Insurance | ||
Private insurance | 1.1 (0.93-1.3) | 0.29 |
Initial blood analysis | ||
Procalcitonin (<0.1 ng/L Reference group) | ||
Procalcitonin 0.1-0.25 ng/L | 0.97 (0.77-1.21) | 0.76 |
Procalcitonin 0.25-0.5 ng/L | 0.78 (0.6-1.01) | 0.06 |
Procalcitonin >0.5 ng/L | 0.69 (0.56-0.85) | <0.001 |
C-reactive protein (<50 mg/L Reference group) | ||
C-reactive protein 50–100 mg/L | 0.76 (0.6-0.96) | 0.02 |
C-reactive protein 100–150 mg/L | 1.03 (0.82-1.28) | 0.82 |
C-reactive protein > 150 mg/L | 0.78 (0.65-0.94) | 0.01 |
Initial albumin level <30 g/L | 0.80 (0.67-0.96) | 0.02 |
Initial sodium <130 or >140 mmol/L | 0.89 (0.76-1.04) | 0.17 |
Severity of CAP | ||
Bacteremic CAP | 0.74 (0.58-0.95) | 0.02 |
Multilobar CAP | 0.73 (0.56-0.93) | 0.01 |
Development of empyema | 0.41 (0.28-0.6) | <0.001 |
ICU transfer during hospitalisation | 0.45 (35–0.59) | <0.001 |
Pneumonia severity index | ||
PSI class (per increase in PSI class) | 0.71 (0.66-0.75) | <0.001 |