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Table 4 Relative change in hs-cTnT (95% confidence interval) by changing covariables on admission for Acute Exacerbation of COPD

From: Determinants of high-sensitivity cardiac troponin T during acute exacerbation of chronic obstructive pulmonary disease: a prospective cohort study

  

Model 1

Model 2

Covariable

Change in covariable

Relative change in hs-cTnT

p -value

Relative change in hs-cTnT

p -value

Time independent

     

  Age at inclusion

+5 years

1.24 (1.13 – 1.37)

<0.0001

1.19 (1.08 – 1.31)

0.0005

  History of HT

Yes vs. no

1.44 (1.03 – 2.01)

0.034

1.29 (0.92 – 1.80)

0.138

Time dependent

     

  Heart rate ≥100/min

Yes vs. no

1.25 (1.01 – 1.54)

0.042

1.24 (1.02 – 1.52)

0.036

  Creatinine

+10 μmol/L

1.05 (1.003 – 1.09)

0.037

1.04 (1.002 – 1.09)

0.037

  Time since inclusion

+1 month

1.02 (1.0004 – 1.05)

0.046

1.02 (0.99 – 1.05)

0.051

  1. Obtained from a linear mixed model using 202 admissions among 94 patients.
  2. Model 1 is adjusted for gender, hypoxemia, and BMI <20 kg/m2. Model 2 is additionally adjusted for survival status. hs-cTnT, high-sensitivity cardiac troponin T; HT, arterial hypertension.