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Table 1 Characteristics, haemodynamics and Cardiopulmonary exercise parameters at baseline of the overall group (n = 116) and between patients with PAH (n = 85) and those with CTEPH (n = 31)

From: Ventilatory efficiency testing as prognostic value in patients with pulmonary hypertension

 

Overall

PAH

CTEPH

p

 

(n = 116)

(n = 85)

(n = 31)

 

Age (years)

61.5 ± 1.5

59.9 ± 1.9

66.4 ± 2.0

p = 0.064

Sex (% female)

66

70

55

ns

BMI (kg/m2)

25.8 ± 0.5

25.7 ± 0.6

26.2 ± 0.7

ns

PAP, mmHg

39.9 ± 2.5

40.5 ± 1.7

38.3 ± 3.1

ns

CI, L*min-1*m-2

2.48 ± 0.07

2.58 ± 0.08

2.22 ± 0.11

p = 0.021

PVR, dynes * s * cm-5

648.2 ± 40.2

647.9 ± 45.1

648.9 ± 87.5ns

 

RAP, mmHg

7.28 ± 0.49

7.01 ± 0.56

8.07 ± 1.00

ns

W, watts

56.2 ± 3.1

55.2 ± 3.7

59.1 ± 5.5

ns

VO2, ml/min/kg

14.4 ± 0.7

14.5 ± 0.8

14.1 ± 1.2

ns

AT, ml/min/kg

9.53 ± 0.40

9.56 ± 0.48

9.45 ± 0.72

ns

O2 pulse, ml/min/beat

8.98 ± 0.36

8.71 ± 0.40

9.72 ± 0.81

ns

Ve/VO2 - AT

41.1 ± 1.1

40.9 ± 1.2

41.8 ± 2.3

ns

Ve/VCO2 - AT

47.2 ± 1.1

47.0 ± 1.2

47.8 ± 2.5

ns

AaDO2 (peak exercise)

mmHg 49.3 ± 1.6

51.6 ± 1.9

43.2 ± 2.9

p = 0.019

a-et CO2, mmHg

5.7 ± 0.5

5.2 ± 0.5

7.0 ± 1.0

ns

Ve/VCO2 slope

46.9 ± 2.0

46.6 ± 2.3

47.9 ± 3.9

ns

  1. W = work capacity.
  2. VO2 = peak oxygen uptake.
  3. AT = anaerobic threshold.
  4. O2 pulse = oxygen pulse.
  5. Ve/VO2 = oxygen equivalent at anaerobic threshold.
  6. Ve/VCO2 = carbon dioxide equivalent at anaerobic threshold.
  7. AaDO2 = alveolar-arterial oxygen difference at peak exercise.
  8. a-et CO2 = arterial-endexpiratory carbon dioxide difference at peak pexercise.
  9. Ve – VCO2 slope = slope of minute ventilation versus carbon dioxide output.