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Figure 3 | BMC Pulmonary Medicine

Figure 3

From: Pirfenidone inhibits TGF-β1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells

Figure 3

Effects of pirfenidone on collagen type I and HSP47 mRNA expression in A549 cells. Northern blots show that mRNA expression of collagen type I (a) and HSP47 (b) was inhibited in A549 cells after 6 and 48 h of incubation, with 500 and 1000 μg/ml, respectively, of pirfenidone and 5 ng/ml of TGF-β1. Density of mRNA bands was normalized against GAPDH mRNA band and is shown as ratios (c and d). Values are means ± SEM of 4 experiments.

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BMC Pulmonary Medicine

ISSN: 1471-2466

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