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Figure 4 | BMC Pulmonary Medicine

Figure 4

From: Pirfenidone inhibits TGF-β1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells

Figure 4

Immunocytochemistry of collagen type I and HSP47 expression in A549 cells stimulated with TGF-β1 (5 ng/ml) and 0 (a, e), 100 (b, f), 500 (c, g), and 1000 μg/ml (d, h) of pirfenidone, respectively for 48 h. Original magnification: x400. Positive rates for collagen type I (i) and HSP47 (j) immunostained A549 cells were significantly inhibited by 100, 500, 1000 μg/ml and by 500 and 1000 μg/ml of pirfenidone, respectively. Values are means ± SEM of 5 experiments.

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