Figure 6

Effects of pirfenidone on morphological changes stimulated by TGF-β1 for 48 h in A549 cells. (a) Untreated A549 cells show a pebble-like epithelial shape (a) and TGF-β1-treated cells show a spindle-like mesenchymal shape (b). Pirfenidone partially suppresses TGF-β1-induced mesenchymal morphology (c).