Genetic influences on right ventricular systolic pressure (RVSP) in chronic obstructive pulmonary disease (COPD)

Table 5 Association of genotype groups with KCO % predicted, in COPD patients with a KCO measurement, using ANOVA

Gene	Genotypes	Number	Mean KCO % predicted	Standard Deviation	Pvalue
VEGFA	GG	241	58.4	23.0	0.88
	GC	244	57.7	21.8
	CC	73	59.1	23.9
		Total 558		22.6
NOS3-VNTR	4bb	401	58.1	22.9	0.36
	4ab	142	59.1	21.5
	4aa	15	50.3	24.5
		Total 558		22.6
ACE	II	136	60.3	24.9	0.42
	ID	273	57.3	22.1
	DD	150	57.6	21.2
		Total 559		22.6
SLC6A4	LL	176	58.0	22.4	0.84
	LS	275	58.7	22.8
	SS	101	57.2	22.0
		Total 552		22.5
PTGIS	CC	327	58.5	21.4	0.11
	CA	192	56.2	23.8
	AA	40	64.3	25.0
		Total 559		22.6
NOS3-298	GG	250	58.5	24.0	0.10
	GT	265	58.9	21.7
	TT	41	50.9	16.7
		Total 556
EDN1	GG	310	57.5	22.4	0.17
	GT	173	57.5	22.7
	TT	40	64.6	24.5
		Total 523		22.7