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Table 5 Association of genotype groups with KCO % predicted, in COPD patients with a KCO measurement, using ANOVA

From: Genetic influences on right ventricular systolic pressure (RVSP) in chronic obstructive pulmonary disease (COPD)

Gene Genotypes Number Mean KCO % predicted Standard Deviation Pvalue
VEGFA GG 241 58.4 23.0 0.88
  GC 244 57.7 21.8  
  CC 73 59.1 23.9  
   Total 558   22.6  
NOS3-VNTR 4bb 401 58.1 22.9 0.36
  4ab 142 59.1 21.5  
  4aa 15 50.3 24.5  
   Total 558   22.6  
ACE II 136 60.3 24.9 0.42
  ID 273 57.3 22.1  
  DD 150 57.6 21.2  
   Total 559   22.6  
SLC6A4 LL 176 58.0 22.4 0.84
  LS 275 58.7 22.8  
  SS 101 57.2 22.0  
   Total 552   22.5  
PTGIS CC 327 58.5 21.4 0.11
  CA 192 56.2 23.8  
  AA 40 64.3 25.0  
   Total 559   22.6  
NOS3-298 GG 250 58.5 24.0 0.10
  GT 265 58.9 21.7  
  TT 41 50.9 16.7  
   Total 556    
EDN1 GG 310 57.5 22.4 0.17
  GT 173 57.5 22.7  
  TT 40 64.6 24.5  
   Total 523   22.7  
  1. Some samples could not be genotyped, making the totals less than 580.
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BMC Pulmonary Medicine

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