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Table 2 Prevalence of comorbidities: adults ≥45 with and without physician-diagnosed COPD: NHANES 1999–2008

From: The prevalence of clinically-relevant comorbid conditions in patients with physician-diagnosed COPD: a cross-sectional study using data from NHANES 1999–2008

Conditions

Without COPD

With COPD

P-valuec

(n = 14,828)a

(n = 995)b

Diseases

CHF, %, (95% CI)

3.9 (3.6–4.3)

12.1 (9.8–14.8)

<.0001

CHD, %, (95% CI)

6.1 (5.5–6.7)

12.7 (10.5–15.3)

<.0001

HTN, %, (95% CI)

52.2 (50.7–53.7)

60.4 (55.8–64.8)

0.0006

High cholesterol, %, (95% CI)

41.3 (39.9–42.6)

47.6 (43.0–52.2)

0.0096

CVA, %, (95% CI)

4.6 (4.2–5.0)

8.9 (7.0–11.1)

<.0001

Diabetes, %, (95% CI)

12.8 (12.1–13.7)

16.3 (13.3–19.8)

0.0184

Osteoporosis, %, (95% CI)

8.5 (7.8–9.2)

16.9 (13.7–20.7)

<.0001

Arthritis, %, (95% CI)

36.9 (35.6–38.2)

54.6 (49.8–59.3)

<.0001

Cancer, %, (95% CI)

9.9 (9.3–10.6)

16.5 (14.2–19.0)

<.0001

Depression, %, (95% CI)

12.5 (11.8–13.3)

20.6 (17.1–24.6)

<.0001

Anxiety, %, (95% CI)

3.8 (3.3–4.3)

8.6 (6.6–11.1)

<.0001

Clinical Factors

Dizziness/Balance Problems, %, (95% CI)d

23.8 (22.4–25.4)

41.1 (36.3–46.1)

<.0001

Obesity, %, (95% CI)

33.5 (32.0–35.1)

40.3 (36.4–44.4)

0.0013

Urinary Incontinence, %, (95% CI)

27.3 (26.1–28.7)

34.9 (29.6–40.5)

0.0048

Anemia, %, (95% CI)

6.2 (5.5–7.1)

9.3 (7.1–12.0)

0.0030

Low GFR, %, (95% CI)

10.5 (9.7–11.2)

16.2 (13.3–19.5)

<.0001

>4 meds, %, (95% CI)

32.1 (30.5–33.8)

51.8 (46.2–57.2)

0.0022

Frailty, %, (95% CI)

3.1 (2.7–3.6)

9.5 (7.0–12.8)

<.0001

Health Status Factors

Memory problems, %, (95% CI)

8.8 (8.1–9.5)

18.5 (14.9–22.7)

<.0001

Mobility difficulty, %, (95% CI)

32.5 (30.7–34.4)

55.6 (50.6–60.5)

<.0001

Hearing impairment, %, (95% CI)

8.3 (7.7–8.9)

12.1 (9.8–14.9)

0.0008

Visual impairment, %, (95% CI)

9.6 (9.0–10.3)

14.0 (12.0–16.2)

<.0001

All Conditions

> = 1 comorbid condition, %, (95% CI)

87.7 (86.4–88.8)

96.4 (94.3–97.8)

<.0001

  1. a Represents ~100 million noninstitutionalized US civilians.
  2. b Represents ~10 million noninstitutionalized US civilians.
  3. c The Bonferroni-corrected significance level, α, is 0.0011.
  4. d Only assessed 1999–2004.