Table 2 Relationship between FEV1 percent predicted and biomarkers in CF subjects per 1 log increase in the biomarkers (n = 58)
Unadjusted | Adjusted* | Standardized Beta-Coefficient (per 1 SD increase in the levels of biomarker) | |||
|---|---|---|---|---|---|
Biomarker | β ± SE | P-value | β ± SE | P-value | |
CRP, mg/L | -10.61 ± 2.65 | < 0.01 | -7.04 ± 1.98 | < 0.01 | -0.3134 |
IL-6, pg/mL | -10.72 ± 3.11 | < 0.01 | -5.53 ± 2.66 | 0.04 | -0.2159 |
IL-1β, pg/mL | -6.97 ± 3.36 | 0.04 | -4.65 ± 2.67 | < 0.01 | -0.1784 |
SP-D, μg/mL | -17.70 ± 7.95 | 0.03 | -9.83 ± 5.93 | 0.10 | -0.1584 |
CCL18, pg/mL | -6.33 ± 5.93 | 0.29 | -3.01 ± 4.23 | 0.48 | -0.0672 |
GzmB, pg/mL | 4.09 ± 2.27 | 0.08 | -0.33 ± 1.89 | 0.86 | -0.0187 |
LPS, pg/mL | 1.07 ± 7.44 | 0.89 | 13.30 ± 5.41 | 0.02 | 0.0239 |
sCD14, μg/mL | 1.88 ± 9.67 | 0.85 | -10.26 ± 6.96 | 0.15 | -0.1414 |
LBP, μg/mL | -22.28 ± 6.63 | < 0.01 | -16.02 ± 4.74 | < 0.01 | -0.2946 |