Table 3 Geometric means (and interquartile ranges) of biomarkers in CF patients who were and were not previously hospitalized
Biomarker | Total (n = 58)* | Previously hospitalized (n = 21)* | Not previously hospitalized (n = 37)* | P-value | Adjusted P-value† | c-statistics |
|---|---|---|---|---|---|---|
CRP, μg/mL | 3.0 (1.5, 6.1) | 3.5 (2.0, 8.0) | 2.8 (1.3, 5.6) | 0.50 | 0.51 | 0.795 |
IL-6, pg/mL | 2.2 (1.1, 4.2) | 3.6 (2.8, 5.8) | 1.7 (1.0, 3.1) | < 0.01 | 0.07 | 0.837 |
IL-1β, pg/mL | 0.16 (0.06, 0.29) | 0.19 (0.06, 0.50) | 0.10 (0.06, 0.20) | < 0.01 | 0.06 | 0.828 |
SP-D, ng/mL | 84.3 (64.0, 112.3) | 87.5 (75.3, 106.1) | 82.6 (63.7, 113.2) | 0.60 | 0.26 | 0.804 |
CCL18, ng/mL | 59.5 (41.4, 75.3) | 60.1 (38.7, 73.5) | 59.2 (44.5, 75.9) | 0.92 | 0.92 | 0.797 |
GzmB, pg/ml | 109.2 (25.5, 389.8) | 90.7 (25.4, 384.9) | 121.2 (26.2, 389.8) | 0.46 | 0.83 | 0.792 |
LPS, ng/mL | 1.1 (0.9, 1.3) | 1.3 (1.0, 1.4) | 1.0 (0.8, 1.3) | 0.01 | 0.04 | 0.841 |
sCD14, μg/mL | 1.1 (0.9, 1.3) | 1.1 (1.0, 1.3) | 1.1 (0.8, 1.3) | 0.89 | 0.49 | 0.789 |
LBP, μg/mL | 27.6 (22.0, 39.9) | 30.8 (23.7, 41.2) | 25.9 (18.8, 35.7) | 0.17 | 0.79 | 0.781 |