Table 1 Analysis of the individual amino acids involved in the cleavages of elastin
Hydrophobocity | Amino acid type | Share of elastin* | No. of cleavages in the N-terminal | No. of cleavages in the C-terminal | Percentage of cleavages | ||||
|---|---|---|---|---|---|---|---|---|---|
R-COOH↓ | ↓NH2-R | R-COOH↓ | ↓NH2-R | R-COOH↓ | ↓NH2-R | Total | |||
Hydrofobic | A | 21% | 15 | 30 | 16 | 36 | 14% | 29% | 21% |
P | 13% | 5 | 5 | 4 | 4 | 4% | 4% | 4% | |
V | 12% | 5 | 37 | 2 | 12 | 3% | 22% | 12% | |
L | 7% | 8 | 5 | 3 | 2 | 5% | 3% | 4% | |
I | 2% | – | 3 | – | 1 | <1% | 2% | 1% | |
F | 2% | 4 | 3 | – | 15 | 2% | 8% | 5% | |
Total | 57% | 27% | 67% | 47% | |||||
Hydrophilic | G | 28% | 71 | 22 | 56 | 33 | 56% | 24% | 40% |
K | 4% | 3 | – | 21 | – | 11% | <1% | 5% | |
S | 2% | – | – | – | 2 | <1% | 1% | <1% | |
Y | 2% | 1 | 3 | – | 2 | <1% | 2% | 1% | |
T | 2% | 1 | 1 | – | 5 | <1% | 3% | 2% | |
R | 2% | – | 4 | 12 | – | <1% | 2% | 4% | |
Q | 1% | – | – | – | 2 | <1% | 1% | <1% | |
Total | 43% | 73% | 33% | 53% | |||||