Table 3 Peptides cleaved at amino acid no. 441 identified by MS in elastin purified from human aorta cleaved in vitro by MMP-9 and -12
Amino acid no. | Identified peptides in elastin from aorta | MMP-9 cleaved (hours) | MMP-12 cleaved (hours) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
2 | 24 | 48 | 72 | ≥169 | 2 | 24 | 48 | 72 | ≥169 | ||
423-441 | VGGVPGVGGVPGVGISPEA | x | |||||||||
425-441 | GVPGVGGVPGVGISPEA | x | x | x | x | ||||||