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Table 4 Peptides cleaved at amino acid no. 441 identified by MS in MS in human vascular wall cleaved in vitro by MMP9

From: Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation

Amino acid no.

Identified peptide in vascular wall

MMP-9 cleaved (hours)

24

72

168

240

409-441

VGVGGIPGVAGVPSVGGVPGVGGVPGVGISPEA

  

x

 

417-441

VAGVPSVGGVPGVGGVPGVGISPEA

  

x

x

422-441

SVGGVPGVGGVPGVGISPEA

   

x

423-441

VGGVPGVGGVPGVGISPEA

  

x