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Table 4 Changes before and after nCPAP treatment in 10 patients with severe OSAS

From: Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment

 

Baseline

After C-PAP

P

Body Mass Index (kg/m2)

35.3±5.4

36.0±6.0

NS

AHI (events/h)

43.4±12.6

7±5

0.000

ODI (events/h)

35.8±23.5

2.8±1.6

0.002

Average SaO 2 (%)

91.8±3.7

97±1

0.001

Urinary 8-iso-PGF2α (pg/mg creatinine)

350.5±43.3

269.6±48.4

0.007

sNOX2-dp (pg/ml)

38.2±7.4

29±3.2

0.003

Serum NOx (uM/ml)

23.9±3.23

27.3±5

NS

FMD (%)

3.64±4.2

7.0±4.7

0.015