Reduced rhinovirus-specific antibodies are associated with acute exacerbations of chronic obstructive pulmonary disease requiring hospitalisation

Table 3 Factors associated with exacerbation frequency

Univariate analysis	β	p	95% CI for β
*FEV1 % predicted	−1.664	0.002	−2.700 – −0.628
*anti-VP1 IgG₁ levels	−0.440	0.001	−0.700 – −0.179
Use of inhaled steroids	0.978	0.092	−0.164 – 2.119
*Multivariate analysis*	β	p	*95% CI for β*
*FEV1 % predicted	−1.388	0.007	−2.378 – −0.398
*anti-VP1 IgG₁ levels	−0.374	0.004	−0.625 – −0.123

* variables were natural log-transformed.
Only variables with p < 0.01 are shown in the table. r² of the multivariate linear regression = 0.266.

ISSN: 1471-2466