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Figure 1 | BMC Pulmonary Medicine

Figure 1

From: The ACE gene D/I polymorphism as a modulator of severity of cystic fibrosis

Figure 1

Association of clinical data, with numerical distribution, with ACE gene D/I polymorphism and subgroups of CFTR mutations. a Bloxplot denoting the association of the ACE gene D/I polymorphism in patients without taking CFTR gene into account. There were significant differences between groups of patients with the genotypes D/D and I/I. # p: 0.092 * p: 0.768, ¥ p: 0.045. b. Bloxplot denoting the association of the ACE gene D/I polymorphism in the subgroup of patients for whom one class I, II and III mutation have been identified. There were significant differences between groups of patients with genotypes D/D and I/I. # p: 0.478, * p: 0.183; ¥ p: 0.043. c. Bloxplot denoting the association of the ACE gene D/I polymorphism in the subgroup of patients for whom two class I, II and/or III mutation have been identified. There were significant differences between groups of patients with genotype D/D and I/I. # p: 0.789 * p: 0.505; ¥ p: 0.05. Analysis was performed by Mann–Whitney test considering a p-value of 0.05 as statistically significant

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