Skip to main content

Table 2 Multivariate logistic regression analysis of covariates for the risk of 28-day mortality in ALI patients

From: Early intravenous unfractionated heparin and outcome in acute lung injury and acute respiratory distress syndrome – a retrospective propensity matched cohort study

  OR (95% CI) Pvalue*
Age 1.02 (1.00/1.03) 0.002
Male 1.39 (0.92/1.86) 0.13
APACHE II score 1.09 (1.06/1.12) < 0.001
Medical 1.94 (1.34/2.81) < 0.001
Surgery Elective 0.40 (0.25/0.65) < 0.001
Surgery Emergency 0.91 (0.57/1.45) 0.68
Medical conditions
Multiple Trauma 0.51 (0.22/1.15) 0.11
Sepsis 1.27 (0.84/1.90) 0.25
Diabetes 1.83 (1.18/2.83) 0.006
Liver Failure 3.82 (1.48/9.82) 0.006
Hematological malignancy 1.77 (0.89/3.49) 0.10
Aspiration 1.35 (0.63/2.91) 0.44
Pancreatitis 0.67 (0.19/2.38) 0.54
Pneumonia 1.14 (0.75/1.71) 0.55
COPD 1.26 (0.76/2.07) 0.37
Auto immune disease 1.95 (1.07/3.56) 0.03
Previous Myocardial infarction 1.25 (0.83/1.89) 0.29
Immune Compromised 1.69 (1.00/2.83) 0.05
Massive Transfusion 0.68 (0.40/1.16) 0.16
Life support measures
Respiratory failure at admission 1.00 (0.98/1.02) 0.99
Cardiovascular failure (inotropic at admission) 1.00 (0.98/1.02) 0.84
Co interventions
Activated Protein C 1.40 (0.59/3.29) 0.45
Stress dose steroids 1.89 (1.34/2.64) < 0.001
Protective mechanical ventilation (<8 ml/kg) 0.63 (0.45/0.89) 0.008
Restrictive fluid strategy (net fluid balance first 7 days ≤ 0 ml) 0.33 (0.22/0.49) < 0.001
  1. * Potentially confounder (p value ≤ 0.10). COPD = chronic obstructive pulmonary disease, OR = odds ratio, CI = 95% confidence limit.