|
Age
|
1.02 (1.00/1.03)
|
0.002
|
|
Male
|
1.39 (0.92/1.86)
|
0.13
|
|
APACHE II score
|
1.09 (1.06/1.12)
|
< 0.001
|
|
Medical
|
1.94 (1.34/2.81)
|
< 0.001
|
|
Surgery Elective
|
0.40 (0.25/0.65)
|
< 0.001
|
|
Surgery Emergency
|
0.91 (0.57/1.45)
|
0.68
|
|
Medical conditions
|
|
Multiple Trauma
|
0.51 (0.22/1.15)
|
0.11
|
|
Sepsis
|
1.27 (0.84/1.90)
|
0.25
|
|
Diabetes
|
1.83 (1.18/2.83)
|
0.006
|
|
Liver Failure
|
3.82 (1.48/9.82)
|
0.006
|
|
Hematological malignancy
|
1.77 (0.89/3.49)
|
0.10
|
|
Aspiration
|
1.35 (0.63/2.91)
|
0.44
|
|
Pancreatitis
|
0.67 (0.19/2.38)
|
0.54
|
|
Pneumonia
|
1.14 (0.75/1.71)
|
0.55
|
|
COPD
|
1.26 (0.76/2.07)
|
0.37
|
|
Auto immune disease
|
1.95 (1.07/3.56)
|
0.03
|
|
Previous Myocardial infarction
|
1.25 (0.83/1.89)
|
0.29
|
|
Immune Compromised
|
1.69 (1.00/2.83)
|
0.05
|
|
Massive Transfusion
|
0.68 (0.40/1.16)
|
0.16
|
|
Life support measures
|
|
Respiratory failure at admission
|
1.00 (0.98/1.02)
|
0.99
|
|
Cardiovascular failure (inotropic at admission)
|
1.00 (0.98/1.02)
|
0.84
|
|
Co interventions
|
|
Activated Protein C
|
1.40 (0.59/3.29)
|
0.45
|
|
Stress dose steroids
|
1.89 (1.34/2.64)
|
< 0.001
|
|
Protective mechanical ventilation (<8 ml/kg)
|
0.63 (0.45/0.89)
|
0.008
|
|
Restrictive fluid strategy (net fluid balance first 7 days ≤ 0 ml)
|
0.33 (0.22/0.49)
|
< 0.001
|
