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Table 1 Baseline characteristics of the study population according to disease status

From: Prevalence and correlations with depression, anxiety, and other features in outpatients with chronic obstructive pulmonary disease in China: a cross-sectional case control study

Variables

Groups

pValue

 

COPD (n = 1100)

Controls (n = 1100)

 

Number (Percentage, %)

Female sex

273 (24.8)

273 (24.8)

≥0.05

Educated level to high school or beyond

21 (1.9)

21 (1.9)

≥0.05

Smoking history

Past smoker

264 (24.0)

12 (1.1)

<0.05

Current smoker

226 (20.5)

235 (21.4)

 

Never smoker

610 (55.5)

853 (77.5)

 

HADS-A ≥ 8

201 (18.3)

58 (5.3)

<0.05

HADS-D ≥ 8

393 (35.7)

79 (7.2)

<0.05

Mean (SD) or median (quartile)

Age

63.2 (40–75)

62.1 (39–76)

≥0.05

Average number of family members

2.86 (1–4)

2.86 (1–4)

≥0.05

Annual net income per family (yuan)

17002 (440)

17477 (469)

<0.05

BMI (kg/m2)

23.3 (2.8)

23.4 (3.0)

≥0.05

FEV1(L)

1.27 (0.36)

2.55 (0.68)

<0.05

FEV1, % of predicted value

45.2 (10.8)

88.6 (9.2)

<0.05

FEV1/FVC

47.9 (11.5)

83.6 (9.3)

<0.05

6MWD (m)

445.0 (91.0)

580.1 (99.8)

<0.05

HADS-A score

4.8 (2.3)

3.1 (1.6)

<0.05

HADS-D score

5.4 (2.6)

3.5 (2.4)

<0.05

  1. HADS: Hospital Anxiety and Depression Scale: HADS-A: HADS—anxiety; HADS-D: HADS—depression; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; BMI:body mass index; 6MWD: six-minute walking distance; MRC: Medical Research Council; SGRQ: Saint George’s Respiratory Questionnaire: BODE: body mass index, degree of airway obstruction, dyspnea and exercise capacity; Possible anxiety (8 ≤ HADS-A ≤ l0) and probable anxiety (HADS-A ≥ 11) were combined and referred to as anxiety (HADS-A ≥ 8). Possible depression (8 ≤ HADS-D ≤ l0) and probable depression (HADS-D ≥ 11) were combined and referred to and as depression (HADS-D ≥ 8).