Table 3 Disease-related characteristics of the COPD patients according to anxiety or depression status
| Â | Anxiety status | pValue | Depression status | pValue | ||
|---|---|---|---|---|---|---|
| Â | Yes (n = 201) | No (n = 899) | Â | Yes (n = 393) | No (n = 707) | Â |
HADS-A score (mean, sd) | 10.4(3.1) | 3.5(2.1) | <0.05 | NA | NA | NA |
HADS-D score (mean, sd) | NA | NA | NA | 10.5(3.6) | 4.1(3.3) | <0.05 |
BMI (kg/m2) (mean, sd) | 22.5(2.7) | 23.7(2.8) | <0.05 | 23.4(2.9) | 22.2(3.0) | <0.05 |
FEV1 (L) | 1.29(0.35) | 1.30(0.33) | >0.05 | 1.25(0.34) | 1.29(0.35) | <0.05 |
6MWD (m) (mean, sd) | 408.5(78.6) | 456.8 (95.5) | <0.05 | 401.5(88.5) | 460.6(100.5) | <0.05 |
MRC score (mean, 5th-95th) | 2(0–4) | 1(0–2) | <0.05 | 2(0–4) | 1(0–2) | <0.05 |
BODE index (mean, 5th-95th) | 4(1–8) | 2.5(1–6) | <0.05 | 3.5(1–8) | 2.5(1–6) | <0.05 |
SGRQ score (mean, 5th-95th) | ||||||
 Symptom | 72.5(19.5) | 63.5(21.0) | <0.05 | 70.0(17.5) | 62.0(18.7) | <0.05 |
 Activity | 66.3(16.8) | 48.0(18.4) | <0.05 | 61.3(17.5) | 47.8(19.5) | <0.05 |
 Effect | 56.6(18.2) | 32.0(15.4) | <0.05 | 48.0(18.6) | 30.7(18.8) | <0.05 |
 Total | 61.5(17.3) | 40.6(16.4) | <0.05 | 55.3(16.2) | 40.4(17.8) | <0.05 |
COPD severity (Percentage%) | ||||||
 I | 14(7.0) | 149(16.6) | <0.05 | 25(6.4) | 138(19.5) | <0.05 |
 II | 70(34.8) | 390(43.4) | <0.05 | 118(30.0) | 342(48.4) | <0.05 |
 III | 65(32.3) | 224(24.9) | <0.05 | 123(31.3) | 166(23.5) | <0.05 |
 IV | 52(25.9) | 136(15.1) | <0.05 | 127(32.3) | 61(8.6) | <0.05 |
Comorbid anxiety | NA | NA | NA | 165(42.0) | 36(5.1) | <0.05 |
Comorbid depression | 145(72.1) | 248(27.6) | <0.05 | NA | NA | NA |
Female sex | 41(20.4) | 232(25.8) | <0.05 | 112(28.5) | 161(22.7) | <0.05 |