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Table 3 Sensitivity, specificity, and positive and negative predictive values for PET-positivity at consecutive cut-off points of the prediction rule score

From: A predictive tool for an effective use of 18F-FDG PET in assessing activity of sarcoidosis

Prediction rule cut-off point* Sensitivity (%)** Specificity (%)** Positive predictive value (%)** Negative predictive value (%)** Patients referred for PET (%)***
0 100 (77/77) 0 (0/18) 81 (77/95) - 0 (/95)
1 94.8 (73/77) 27.8 (5/18) 84.8 (73/86) 55.5 (5/9) 9.5 (9/95)
2 93.5 (72/77) 33.3 (6/18) 85.7 (72/84) 54.5 (6/11) 11.6 (11/95)
3 90.9 (70/77) 38.9 (7/18) 86.4 (70/81) 50.0 (7/14) 14.7 (14/95)
4 85.7 (66/77) 55.6 (10/18) 89.2 (66/74) 47.6 (10/21) 22.1 (21/95)
5 81.8 (63/77) 55.6 (10/18) 88.7 (63/71) 41.7 (10/24) 25.3 (24/95)
6 79.2 (61/77) 66.7 (12/18) 91.0 (61/76) 42.9 (12/28) 29.5 (28/95)
7 77.9 (60/77) 72.2 (13/18) 92.3 (60/65) 43.3 (13/30) 31.6 (30/95)
8 76.6 (59/77) 72.2 (13/18) 92.2 (59/64) 41.9 (13/31) 32.6 (31/95)
9 72.7 (56/77) 83.3 (15/18) 94.9 (56/59) 41.7 (15/36) 37.9 (36/95)
10 64.9 (50/77) 94.4 (17/18) 98.0 (50/51) 38.6 (17/44) 46.3 (44/95)
11 53.2 (41/77) 94.4 (17/18) 97.6 (41/42) 32.0 (17/53) 55.8 (53/95)
12 48.1 (37/77) 94.4 (17/18) 97.4 (37/38) 29.8 (17/57) 60.0 (57/95)
13 41.6 (32/77) 94.4 (17/18) 97.0 (32/33) 27.4 (17/62) 65.3 (62/95)
14 35.1 (27/77) 94.4 (17/18) 96.4 (27/28) 25.4 (17/67) 70.5 (67/95)
15 27.3 (21/77) 100 (18/18) 100 (21/21) 24.3 (18/74) 77.9 (74/95)
16 24.6 (19/77) 100 (18/18) 100 (19/19) 23.7 (18/76) 80.0 (76/95)
17 20.8 (16/77) 100 (18/18) 100 (16/16) 22.8 (18/79) 83.2 (79/95)
18 13.0 (10/77) 100 (18/18) 100 (10/10) 21.2 (18/85) 89.5 (85/95)
19 7.8 (6/77) 100 (18/18) 100 (6/6) 20.2 (18/89) 93.7 (89/95)
20 7.8 (6/77) 100 (18/18) 100 (6/6) 20.2 (18/89) 93.7 (89/95)
21 3.9 (3/77) 100 (18/18) 100 (3/3) 19.6 (18/92) 96.8 (92/95)
  1. *Patients were considered test-positive if the prediction rule score was at or above this level.
  2. **Data in parentheses represent proportions.
  3. ***Number of patients that would have been indicated for referral to PET if the prediction rule score was at or above the corresponding level.