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Table 3 Sensitivity, specificity, and positive and negative predictive values for PET-positivity at consecutive cut-off points of the prediction rule score

From: A predictive tool for an effective use of 18F-FDG PET in assessing activity of sarcoidosis

Prediction rule cut-off point*

Sensitivity (%)**

Specificity (%)**

Positive predictive value (%)**

Negative predictive value (%)**

Patients referred for PET (%)***

0

100 (77/77)

0 (0/18)

81 (77/95)

-

0 (/95)

1

94.8 (73/77)

27.8 (5/18)

84.8 (73/86)

55.5 (5/9)

9.5 (9/95)

2

93.5 (72/77)

33.3 (6/18)

85.7 (72/84)

54.5 (6/11)

11.6 (11/95)

3

90.9 (70/77)

38.9 (7/18)

86.4 (70/81)

50.0 (7/14)

14.7 (14/95)

4

85.7 (66/77)

55.6 (10/18)

89.2 (66/74)

47.6 (10/21)

22.1 (21/95)

5

81.8 (63/77)

55.6 (10/18)

88.7 (63/71)

41.7 (10/24)

25.3 (24/95)

6

79.2 (61/77)

66.7 (12/18)

91.0 (61/76)

42.9 (12/28)

29.5 (28/95)

7

77.9 (60/77)

72.2 (13/18)

92.3 (60/65)

43.3 (13/30)

31.6 (30/95)

8

76.6 (59/77)

72.2 (13/18)

92.2 (59/64)

41.9 (13/31)

32.6 (31/95)

9

72.7 (56/77)

83.3 (15/18)

94.9 (56/59)

41.7 (15/36)

37.9 (36/95)

10

64.9 (50/77)

94.4 (17/18)

98.0 (50/51)

38.6 (17/44)

46.3 (44/95)

11

53.2 (41/77)

94.4 (17/18)

97.6 (41/42)

32.0 (17/53)

55.8 (53/95)

12

48.1 (37/77)

94.4 (17/18)

97.4 (37/38)

29.8 (17/57)

60.0 (57/95)

13

41.6 (32/77)

94.4 (17/18)

97.0 (32/33)

27.4 (17/62)

65.3 (62/95)

14

35.1 (27/77)

94.4 (17/18)

96.4 (27/28)

25.4 (17/67)

70.5 (67/95)

15

27.3 (21/77)

100 (18/18)

100 (21/21)

24.3 (18/74)

77.9 (74/95)

16

24.6 (19/77)

100 (18/18)

100 (19/19)

23.7 (18/76)

80.0 (76/95)

17

20.8 (16/77)

100 (18/18)

100 (16/16)

22.8 (18/79)

83.2 (79/95)

18

13.0 (10/77)

100 (18/18)

100 (10/10)

21.2 (18/85)

89.5 (85/95)

19

7.8 (6/77)

100 (18/18)

100 (6/6)

20.2 (18/89)

93.7 (89/95)

20

7.8 (6/77)

100 (18/18)

100 (6/6)

20.2 (18/89)

93.7 (89/95)

21

3.9 (3/77)

100 (18/18)

100 (3/3)

19.6 (18/92)

96.8 (92/95)

  1. *Patients were considered test-positive if the prediction rule score was at or above this level.
  2. **Data in parentheses represent proportions.
  3. ***Number of patients that would have been indicated for referral to PET if the prediction rule score was at or above the corresponding level.