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Figure 3 | BMC Pulmonary Medicine

Figure 3

From: Interleukin 6, lipopolysaccharide-binding protein and interleukin 10 in the prediction of risk and etiologic patterns in patients with community-acquired pneumonia: results from the German competence network CAPNETZ

Figure 3

Receiver-operating characteristic curves to predict a severe course of community-acquired pneumonia and high CRB-65 or CRB scores. (A) Receiver operator characteristic (ROC) curves for interleukin 6 (IL-6; area under curve (AUC) 0.689; 95% CI 0.636 to 0.741; P < 0.001), lipopolysaccharide-binding protein (LBP; AUC 0.624; 95% CI 0.567 to 0.681; P < 0.0001), interleukin 10 (IL-10; AUC 0.665; CI 0.611 to 0.718; P < 0.0001), CRB score (AUC 0.701; 95% CI 0.643 to 0.760; P < 0.0001) and CRB-65 score (AUC 0.764; 95% CI 0.716 to 0.812; P < 0.0001), and (B) combination of CRB-65 score plus IL-6 concentration (AUC 0.800; 95% CI 0.759 to 0.842; P < 0.0001) and CRB score plus IL-6 concentration (AUC 0.765; 95% CI 0.720 to 0.810; P < 0.0001), in predicting a severe course of community-acquired pneumonia (CAP).

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